- The project is about the relationship between what we eat, our bodily and mental health and how self care can educate and reframe how we access our health data.
- I began by looking at the link between mental health disorders like anxiety and depression and their link to microbiome and how to begin to treat and better understand how to treat this we need to become more comfortable with testing for it
- what was the driver for the paper? you right about how –
- stool can’t be on demand
- research demonstrates that patients are reluctant to handle their own stool and are embarrassed about transporting faeces
- IBD means lots of people can’t comply on demand
- do you find people are more inclined to want to do a rectal swab?
- Studies of patient opinions demonstrate high levels of acceptability for CPE detection and rectal swabbing as a method of sample collection6. Given their acceptability, ease of administration, ease of self-administration and existing utility in clinical microbiology, rectal swabs might represent an attractive means for sampling the broader gut microbiota and aspects of the gut metabolome.
- are swabs comforatble?
- ’multi omics’
NOTES
- multi omics’ uses mass spectronomy
- helps understand more about the relationship between omicron and details
- coun protetant is a protein marker / signifier – the higher the level the worse inflammation you have – this might imply inflammatory bowel disease if low or bowel cancer if high
- What’s the new improves swab – scientific report.
- coupon – designed the swab – 3d printed for accuracy and comfort, ergonomic – balance between getting enough sample and being comfortable – this might change between parts of the world – sized, anatomical variation etc
- The expensive – is there hope for more accessible testing? (Proton nuclear magnetic resonance (1H NMR) spectroscopy enabled the detection of 20 metabolites)
- microbiome profiling isn’t there yet
- blood hemogloban is standardised – machines are calibrated – with gut microbiome: extraction is varied, the control is varied, the sequencing is varied (citizen science stuff like zoe is helping but its not there yet)
- its early stage yet there is already so many commercial entities
- 60 world wide microbiome experts are bringing out a paper about managing expectation – but its early stage – so many commercial entities
- still – could be used as microbiome monitoring
- tech has got cheaper and there is more detail about what bugs are there
- tech has got smaller and starts up can get them etc
THINKING RESEARCH 